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A leukemia drug dasatinib and the dietary supplement quercetin reduced senescent cells' numbers, tamped down the inflammation they cause, and reduced the level of disability that comes with age-related diseases.
The drugs delayed age-related diseases. And the anti-aging effects of a single five-day course of the cocktail lasted for months, the equivalent in humans of more than a decade.
Giving dasatinib-quercitin combo in mice at the age equivalent of 75 to 90 years in humans let them live 36% longer with better physical function.