This comes after more than a year of war against Yemeni Houthi rebels, who have targeted international transit in regional waters.

The incident is highly unusual given that US and Western allied coalition ships have come under repeat drone and missile from from the Houthis, but have thus far suffered no disclosed losses. The Western coalition has reported no damage or casualties from this long-running battle, and yet it appears the first shootdown of an American fighter jet in the conflict has come by way of US aircraft carrier fire.

The two pilots ejected after their F/A-18 fighter was hit and have been safely rescued in Red Sea waters, with one of the pilots suffering injuries.

The Associated Press and ABC News are reporting the following details after official CENTCOM confirmation:

Two U.S. Navy pilots ejected safely over the Red Sea after their F/A-18 fighter aircraft was mistakenly shot down early Sunday in what military officials are calling "an apparent case of friendly fire."

One of the pilots has minor injuries, according to a news release from U.S. Central Command.

The guided-missile cruiser USS Gettysburg, which is part of the USS Harry S. Truman Carrier Strike Group, mistakenly fired on and hit the aircraft, that was flying off the USS Harry S. Truman, according to the news release.

CENTCOM says it is investigating the incident. Again, it is clearly bizarre given the aircraft had just taken off from the same carrier strike group of which the USS Gettysburg is part.

"The F/A-18 shot down had just flown off the deck of the USS Harry S. Truman aircraft carrier," Central Command indicated. 

The US military was conducting an assault against militants in Yemen at the time of the incident. AP details further, "The U.S. military had conducted airstrikes targeting Yemen's Houthi rebels at the time, though the U.S. military's Central Command did not elaborate on what their mission was and did not immediately respond to questions from The Associated Press."

There appears to have been some 'fog of war' confusion given that just prior to the friendly fire shootdown the Houthis had launched drones and a cruise missile at the US battle group. The F-18 may have been mistakenly identified by the Gettysburg warship as an inbound Houthi UAV.