>
At Least 10 Children Killed by Israeli Drones While Waiting Outside Clinic for Medical Aid and Food
IRS Gives Churches Blessing to Endorse Candidates
17 Out-Of-Place Artifacts That Suggest High-Tech Civilizations Existed Thousands (Or Millions)...
Magic mushrooms may hold the secret to longevity: Psilocybin extends lifespan by 57%...
Unitree G1 vs Boston Dynamics Atlas vs Optimus Gen 2 Robot– Who Wins?
LFP Battery Fire Safety: What You NEED to Know
Final Summer Solar Panel Test: Bifacial Optimization. Save Money w/ These Results!
MEDICAL MIRACLE IN JAPAN: Paralyzed Man Stands Again After Revolutionary Stem Cell Treatment!
Insulator Becomes Conducting Semiconductor And Could Make Superelastic Silicone Solar Panels
Slate Truck's Under $20,000 Price Tag Just Became A Political Casualty
Wisdom Teeth Contain Unique Stem Cell That Can Form Cartilage, Neurons, and Heart Tissue
Hay fever breakthrough: 'Molecular shield' blocks allergy trigger at the site
First of all, there already are commercially-available 3D-bioprinted skin grafts, made from living cells. These are typically intended just to be temporary wound coverings, however, as they lack the vasculature that would allow life-giving blood to flow from the patient's body and into them. As a result, such grafts eventually die, sloughing off the patient's own skin.
Looking to overcome this limitation, a team at New York's Rensselaer Polytechnic Institute initially started by mixing two types of living human cells to produce so-called "bio-inks." These were printed into a skin-like structure, although it still lacked a vascular system.
More recently, in collaboration with colleagues at Yale University, they added certain "key elements" to those bio-inks. These elements included human endothelial cells – which line the inside of blood vessels – and human pericyte cells, which wrap around the endothelial cells. These were combined with ingredients that are typically found in bioprinted skin grafts, such as animal collagen and other structural cells.
Within the space of a few weeks, blood vessels began growing in skin that had been printed from the new bio-inks. When these pieces of the skin were grafted over open wounds on mice, the animals' blood vessels began communicating with those in the bioprinted skin, causing the grafts to become perfused with blood after four weeks.