Acting Deputy TSA Administrator Adam Stahl told Fox News that the TSA has "fully depleted" its available workforce from the National Deployment Office to cover staffing shortages at airports.

"So at this point, we're fully stretched. Frankly, there's not much else we can do," he told the news outlet. "As the weeks continue, if this continues, it's not hyperbole to suggest that we may have to quite literally shut down airports, particularly smaller ones."

Stahl said the government shutdown has placed financial strain on TSA workers living paycheck to paycheck, with some sleeping in their cars and drawing blood to pay for expenses.

"If there's not action taken, particularly from Senate Democrats, this is going to get worse," he said. "It's not going to get better, and there will be significant pain for passengers as well. Three [to] four-hour wait time at select airports."

Funding for DHS lapsed last month after Congress failed to strike a deal on immigration reforms sought by Democrats following the fatal shooting of two U.S. citizens by federal immigration agents during operations in Minnesota earlier this year.

The partial shutdown has left about 50,000 TSA officers working without pay. More than 300 officers have quit from the agency during the shutdown, according to DHS.

The department said that just over 10 percent of TSA officers were absent from work on March 15.

The CEOs of major U.S. airlines wrote a joint letter on March 15 urging congressional leaders to come together immediately to negotiate a deal to fund DHS and end the partial government shutdown.

In the letter, the CEOs said it is unacceptable for TSA workers to go without pay, noting that it is "difficult, if not impossible, to put food on the table, put gas in the car and pay rent" when they are not getting paid.

"This problem is solvable, and there are solutions on the table. Now it's up to you, Congress, to move forward on bipartisan proposals that will get federal aviation workers—including TSA officers, U.S. Customs clearance officers at airports and air traffic controllers—paid during shutdowns," the CEOs said.

The previous government shutdown last fall lasted 43 days, causing widespread flight disruptions and forcing the Federal Aviation Administration to order 10 percent reductions at major airports nationwide.