Lindsey Graham's death is poised to upend the Senate, where the GOP majority was already tight and the four-term South Carolina Republican loomed large in several immediate policy fights ahead of the midterms — putting the fate of multiple legislative priorities into question.

Graham — who died of a "brief a sudden illness" Saturday, according to his office — chaired the Budget Committee, which has been facing pressure from President Donald Trump to advance a new party-line spending package including a major boost in defense funding. He was also a senior member of the Appropriations Committee, which has been working to land a deal to avert a government shutdown at the end of September.